Liver Function Test – How To Interpret Strange Results?

For Many big causes of death, such as chest, neoplastic, and cardiovascular disease, mortality is falling. However, deaths due to liver disease are increasing rapidly; between 1970 and 2010 the UK standardised mortality rate for liver disease increased by over 400%.1 The mortality rate for patients under 65 years old increased by nearly 500% over the same period,1 and liver disease is currently the fifth most common cause of premature death in England and Wales. Liver Disorder in adults has three important causes: alcohol abuse; chronic viral hepatitis; and obesity/metabolic syndrome, which might cause non-alcoholic fatty liver disease NAFLD. Much liver disease is preventable and if it is diagnosed early, clinical interventions and lifestyle changes may slow or stop disease development.

Liver function tests

In Its early stages, lft test price in delhi is often asymptomatic–roughly 50 percent of patients with cirrhosis are diagnosed when admitted to hospital with a decompensating occasion, like ascites, bleeding varices, or hepatic encephalopathy. Primary Care has a significant part to play in the prevention and early detection of liver disease, and liver blood tests are an important element of this. In November 2017, the British Society of Gastroenterology BSG printed Guidelines on the management of abnormal liver blood tests. The guideline is intended to be utilised in both primary and secondary care and contains recommendations on

  • How to react to abnormal liver blood test results
  • When liver blood tests should be done

Although Traditionally known as liver function tests LFTs, typical testing panels include measurement of hepatobiliary enzymes along with accurate measures of liver function. For this reason, the BSG advice refers to liver blood tests Instead of LFTs to capture more accurately the significance to clinical practice. There Is no standardised panel for liver blood tests and testing varies between physicians. Liver Blood tests may be a challenge to interpret; results may be normal or near normal even in advanced liver disease, and, when strange, the degree of abnormality may not reflect disease severity–liver blood tests may be abnormal even if there is not any substantial liver disease.3 Standard liver blood test panels could be used routinely when patients have unexplained or non-specific symptoms and in such conditions abnormal results are found in approximately 20 percent of patients.5 The importance of these results is often uncertain and patients are often subject to additional cycles of investigation, yet most patients referred to hospital with abnormal liver blood tests don’t have significant liver disease.

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